Every week, some of our senior researchers in each department at ASDRP give public seminar presenting the current state of the field, and disseminating how their research at ASDRP fits into the broader context of the frontiers of modern science and engineering. Colloquia are public events, and anyone can join. Simply click the Google Calendar link to add the event to your calendar.
Department of Biological, Human & Life Sciences
Tuesdays @ 8:00 - 9:00 PM PST
Tuesday, November 17, 2020
Examining Yogurt Bacterial Strains for Horizontal Gene Transfer.
Lactobacillus bulgaricus and Streptococcus thermophilus are two common strains of bacteria commonly found in yogurt cultures and have been used in yogurt cultures for thousands of years. Protocooperation between the two strains of bacteria is shown to include horizontal gene transfer (HGT), the process in which genetic information is the transfer between prokaryotes. HGT plays a major role in bacteria’s ability to adapt to its environment. This protocooperation has been shown to include horizontal gene transfer (HGT). Here, a general background on horizontal gene transfer and an in-depth overview of the different strains of bacteria found in yogurt will be discussed as well as our laboratory research as a part of the Tallapaka group.
Anika E., Monte Vista High School
Tallapaka Research Group
Department of Chemistry, Biochemistry & Physics
Fridays @ 8:00 - 9:00 PM PST
Friday, November 20, 2020
Synthesis and Structure-Activity Relationship of 2-substituted Benzimidazole KRAS Inhibitors.
Around 1.8 million people in the U.S are diagnosed with cancer, and approximately 600 thousand people die from cancer each year in the United States. The KRAS (Kristin Rat Sarcoma Viral Oncogene Homolog) gene is part of the RAS family of oncogenes, and is found in nearly 22% of all tumors. The KRAS protein is a GTPase and plays a vital role in many signal transduction pathways. Benzimidazoles are heterocyclic aromatic compounds and are a fusion of benzene and imidazole. Benzimidazole derivatives have many pharmaceutical uses and have been shown to exhibit activity against viruses like herpes and human immunodeficiency virus. They are also present in anthelmintic drugs and work as potential antitumor agents. Our research aims to investigate the structure-activity relationship and synthesis of various 2-substituted benzimidazole derivatives as KRAS inhibitors, then test its efficacy through biological assays.
Mathavan M., American High School
Clark Research Group
Department of Computer Science & Engineering
Wednesdays @ 8:00 - 9:00 PM PST
Wednesday, November 18, 2020
Using speech emotion recognition to analyze sentiment in speeches and debates from the 2020 US presidential race.
In today's polarizing political climate, many Americans find it is becoming increasingly difficult to find unbiased and factual information about political candidates and their views. There are varying perspectives on the interpretation of language and speech, especially in a political context. Two different news sources could portray the same instance in very opposing stances. Our proposed solution to this issue is to use Speech Emotion Recognition (SER) to systematically determine political candidates’ sentiment in their speeches and debates. Our version of SER focuses on classifying human speech into one of psychologist Paul Ekman’s proposed “six basic emotions”: happiness, sadness, anger, disgust, fear, or surprise. We will use machine learning and neural networks to accomplish this, using the Ryerson Audio-Visual Database of Emotional Speech and Song as a reference for instances of these emotions, then apply the model to various speeches and debates from the US 2020 presidential race. Our goal is to produce an output that represents the verbal sentiment of the presidential candidates--Donald Trump and Joe Biden--in an accurate and unbiased way.
Eric W., Mountain View High School
Johnson Research Group
Data Science, Environmental Studies