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Student Colloquia

Every week, some of our senior researchers in each department at ASDRP give public seminar presenting the current state of the field, and disseminating how their research at ASDRP fits into the broader context of the frontiers of modern science and engineering. Colloquia are public events, and anyone can join. Simply click the Google Calendar link to add the event to your calendar.

Department of Biological, Human & Life Sciences

Tuesdays @ 8:00 - 9:00 PM PST

Tuesday, December 1, 2020

ASDRP New Safety Laboratory Safety Guidelines

 

ASDRP puts the health and safety of our researchers first. This week's Biology and Life Science Colloquium will focus on  reviewing and having an in depth discussion with Soumya Suresh and Edward Njoo about the recent update to the ASDRP Laboratory Safety Guidelines.

Stay Safe!

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Edward Njoo, ASDRP Leadership Team
Soumya Suresh, ASDRP Leadership Team

Department of Chemistry, Biochemistry & Physics

Fridays @ 8:00 - 9:00 PM PST

Friday, December 4, 2020

Accounting for conformational isomerism in biologically-relevant small molecules, using 19-F Nuclear Magnetic Resonance to probe solvent effects in keto-enol tautomerization, and comparing the efficiency of palladium catalysts in the Carroll rearrangement

Protein-ligand docking is a popular method used in or high throughput virtual screening to evaluate the potential of ligands as effective substrates for a specific protein target in hit-to-lead generation. Although docking is a quick way to screen molecules against a known target, most algorithms treat the ligand and protein as static bodies, failing to account for conformational states, potentially returning false-negatives. To address this, docking algorithms can be run on all conformation states of ligands, but this is a significantly computationally intensive process, as the number of entities in the target and ligand increases exponentially.  Here, an overview of a simplified geometry-based approach to account for conformational isomers will be described. Current work on investigating hydrogen vs deuterium solvent effects and directly observable kinetic isotopic effects on keto-enol tautomerization will also be presented. Further, through the Carroll rearrangement, the relative efficiencies of palladium catalysts with different ligands are being studied in our laboratory and the importance of palladium catalysis in industry will be explored in brief. .

 

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Anvi S., Quarry Lane School

Njoo Research Group

Organic, Medicinal Chemistry

Department of Computer Science & Engineering

Wednesdays @ 8:00 - 9:00 PM PST

Wednesday, December 2, 2020

Sentiment Analysis on Speeches of 2020 Primary Presidential Candidates.

 

Sentiment analysis uses natural language processing, text analysis, and computational linguistics to analyze statements and determine whether they are positive, negative, or neutral about a particular topic or product. Since there are varying levels of polarity, algorithms can be used to assign these levels to statements. A statement's subjectivity can also be determined, allowing the text to be substantiated as fact or opinion. Sentiment analysis has various implications in society. It allows one to analyze people's opinions on a subject relatively quickly compared to reading through texts to figure out the opinion. In addition, the sentiments can help one understand what they can do to improve a product or event based on others' sentiments. In this project, our group will be analyzing speech transcripts of two political leaders, Donald Trump and Joe Biden, to determine their sentiments regarding various topics. We can then figure out how each leader feels or thinks about a subject based on their choice of words. We will create a machine learning model, which will incorporate transcripts of their speeches and determine its sentiment.

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Alex George, Dhruv Suresh, Mahika Modi, and Amulya Chirumamilla.

Johnson Research Group

Data Science, Environmental Studies

Life Science Research & Development Laboratory:

46307 Warm Springs Blvd. Fremont, CA 94539

Engineering Research Laboratory:

46249 Warm Springs Blvd. Fremont, CA 94539

General Inquiries: asdrp.admin@asdrp.org

Admissions: admissions@asdrp.org

Telephone: 1(510)371-4831

© Aspiring Scholars Directed Research Program 2020, All rights reserved.

ASDRP is a production of Olive Children Foundation, a 501(c)(3) nonprofit organization in Fremont, California.

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